RAF Typhoon FGR4s have operated alongside France's air force in a combined operation on an underground arms cache in Syrian territory employed by the Daesh militant organization, per a report from the UK's MoD.
The site, located using reconnaissance, was assessed as containing munitions and bombs, the release indicated, and was located in hills just to the north of the historic site of Palmyra in Syria's central region.
"The RAF jets utilized Paveway IV guided bombs to hit a several access tunnels providing entry to the depot... early reports indicate the objective was successfully hit," officials stated.
There was no sign of any harm to civilians in the attack on Saturday evening and each participating jet returned to base without incident, the defence officials confirmed.
The Typhoon fighters were supported by a Voyager refuelling tanker.
Daesh - alternatively referred to as the so-called Islamic State - established jihadist rule over significant areas in Iraq and Syria until 2019.
"This operation demonstrates our UK leadership, and resolve to work closely with our allies, to eliminate any resurgence of IS and their dangerous and violent ideologies in the area," Britain's Defence Chief John Healey stated.
UK warplanes have carried out overwatch operations over Syrian airspace to "prevent any efforts to regroup" of Islamic State after its defeat at the Baghuz confrontation in 2019, the ministry said.
"I extend gratitude to the personnel of the UK armed forces participating in this operation for their professionalism and their valour," the Defence Secretary said. "They were among numerous British personnel on duty over the festive period. This operation, to take out terrorist threats who threaten our security, highlights how our armed forces are always on standby, throughout the year, keeping Britain secure within its borders and strong abroad."
Last December, the US military executed what it described as a "major assault" targeting IS targets in Syria, after an ambush resulted in the deaths of two US troops and a civilian interpreter in the Palmyra area.
The U.N. reports Islamic State still maintains between 5,000 and 7,000 militants in both countries.